Lung cancer is a type of cancer that begins in the cells of the lungs. It is one of the most common types of cancer and can be life-threatening if not diagnosed and treated early.
The symptoms of lung cancer can vary depending on the type and stage of cancer, but some common symptoms include:
- Persistent cough: A cough that lasts for several weeks and doesn’t go away can be a sign of lung cancer.
- Shortness of breath: This can occur even with mild exertion or at rest.
- Chest pain: Pain in the chest, shoulder, or back can be a sign of lung cancer.
- Hoarseness: A change in the sound of your voice, such as becoming hoarse, can be a sign of lung cancer.
- Weight loss: Unexplained weight loss can be a symptom of lung cancer.
- Fatigue: Feeling tired or weak can be a symptom of lung cancer.
- Wheezing: A high-pitched whistling sound when breathing can be a sign of lung cancer.
It is important to note that some people with lung cancer may not experience any symptoms in the early stages, which is why it is important to undergo regular screening if you are at high risk for developing lung cancer.
Lung cancer screening
Lung cancer screening is a test that is performed on individuals who are at high risk of developing lung cancer. The screening test is usually performed using a low-dose CT (computed tomography) scan, which can detect small abnormalities in the lungs that may indicate the presence of lung cancer.
The main criteria for eligibility for lung cancer screening are:
- Age: Between 55 and 80 years old
- Smoking history: A current smoker or former smoker who quit within the last 15 years
- Smoking intensity: A history of smoking at least one pack of cigarettes per day for 30 years, or two packs per day for 15 years.
It’s important to note that the screening is only recommended for people who are considered at high risk, as the test can also produce false positives, which can lead to unnecessary follow-up testing or treatment.
If you are eligible for lung cancer screening, you should talk to your doctor about the risks and benefits of the screening test, as well as the frequency of the screening. Early detection through lung cancer screening can help increase the chances of successful treatment and recovery.
LORLATINIB 100MG TABLET (LORBRENA)
Lorlatinib, sold under the brand name Lorbrena, is a medication used to treat certain types of advanced non-small cell lung cancer (NSCLC) that have a specific genetic mutation known as anaplastic lymphoma kinase (ALK) or ROS1. It belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs) and works by blocking certain proteins that promote the growth and spread of cancer cells.
Lorbrena 100mg tablet is taken orally in the form of a tablet, usually once daily, with or without food. The dosage and duration of treatment will depend on several factors, including the patient’s overall health, the type and stage of cancer, and their response to the medication.
Like all medications, Lorbrena may cause side effects. Common side effects include fatigue, diarrhea, nausea, vomiting, loss of appetite, cough, headache, and changes in taste. Less common but more serious side effects include lung problems, liver problems, and nerve damage.
It’s important to talk to your doctor about any side effects you experience while taking Lorbrena, as they may be able to recommend ways to manage them or adjust your treatment plan. It’s also important to take the medication as directed and not to stop taking it without first consulting your doctor.
Anaplastic lymphoma kinase (ALK) or ROS1
Anaplastic lymphoma kinase (ALK) and ROS1 are genes that are involved in cell growth and division. Mutations in these genes can cause abnormal activation of the proteins they produce, leading to uncontrolled cell growth and the development of cancer.
In particular, ALK mutations are associated with certain types of non-small cell lung cancer (NSCLC), while ROS1 mutations are found in a smaller subset of NSCLC cases. These mutations can be detected through genetic testing of tumor tissue, which can help guide treatment decisions.
Lung cancer patients with ALK or ROS1 mutations may be eligible for treatment with targeted therapies such as tyrosine kinase inhibitors (TKIs) like lorlatinib (Lorbrena), Crizotinib capsules 250 mg (Crizalk), or Alectinib (Alecensa). These medications work by specifically targeting the proteins produced by the mutated genes, which can help slow or stop the growth of cancer cells. Targeted therapies have been shown to be effective in improving outcomes for patients with ALK or ROS1 mutations.
- What does the symptom of lung cancer depend on?
symptoms of lung cancer can vary depending on the type and stage of cancer
- What are alk?
Anaplastic lymphoma kinase (ALK) and ROS1 are genes that are involved in cell growth and division.
- What is lung cancer screening?
Lung cancer screening is a test that is performed on individuals who are at high risk of developing lung cancer.
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